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Cirrhosis

Cirrhosis is

 

a past due level of scarring (fibrosis) of the liver as a result of many sorts of liver illnesses and conditions, which includes hepatitis and continual alcoholism.
Each time your liver is injured — whether or not with the aid of using disease, immoderate alcohol intake or any other purpose — it attempts to restore itself. In the process, scar tissue forms. As cirrhosis progresses, increasingly scar tissue forms, making it tough for the liver to function (decompensated cirrhosis). Advanced cirrhosis is life-threatening.
The liver harm executed with the aid of using cirrhosis usually can not be undone. But if liver cirrhosis is identified early and the purpose is treated, in addition harm may be restrained and, rarely, reversed.

Symptoms


irrhosis often has no signs or symptoms until liver damage is extensive. If signs and symptoms are present they may include:

tiredness

easy bruising or bleeding

loss of appetite

feeling sick

swelling of the legs, feet or ankles (oedema)

weight loss

itching of the skin

yellowing of the skin Skin and eyes (jaundice)

Accumulation of fluid in the abdomen (ascites)

Spider-shaped blood vessels on the skin

Redness of the palms of the hands

In women, absence or loss of independent periods until menopause

In men, loss of sexual desire, breast enlargement (gynecomastia) or testicular atrophy

confusion, drowsiness and difficulty speaking (hepatic encephalopathy)

when to see a doctor

Make an appointment to see your doctor if you have any of the signs or symptoms listed above.

  • Causes

A variety of diseases and conditions can damage the liver and lead to cirrhosis.
Some of the causes are:

Chronic alcohol abuse

Chronic viral hepatitis (hepatitis B, C, and D)

Fat accumulation in the liver (nonalcoholic fatty liver disease)

Iron accumulation in the body (hemochromatosis)

Cystic fibrosis

Accumulated copper in the Liver (Wilson’s disease)

Malformation of the bile ducts (biliary atresia)

Alpha-1-antitrypsin deficiency

Hereditary disorders of sugar metabolism (galactosemia or glycogen storage)

Genetic digestive disorder (Alagille syndrome)

Liver disease caused by the your body’s immune system & #40; Autoimmune Hepatitis & #41;

Destruction of the bile ducts (primary biliary cirrhosis)

Hardening and scarring of the bile ducts (primary sclerosing cholangitis)

Infection, such as syphilis or brucellosis

Drugs, including methotrexate or isoniazid

Risk factors

Drinking alcohol excessive alcohol consumption is excessive alcohol consumption a risk factor for cirrhosis

Obesity Obesity increases the risk of diseases that can lead to cirrhosis, such as B. non-alcoholic fatty liver disease and non-alcoholic steatohepatitis.have viral hepatitis. Not everyone with chronic hepatitis will develop cirrhosis, but it is a leading cause of liver disease worldwide.

Complications

Complications of cirrhosis can include:

High blood pressure in the veins that supply the liver (portal hypertension). Cirrhosis slows the normal flow of blood through the liver, which increases pressure in the vein that carries blood from the intestines and spleen to the liver.

Swellings in legs and abdomen. Increased pressure in the portal vein can cause fluid to build up in the legs (edema) and abdomen (ascites). Edema and ascites can also be caused by the liver’s inability to produce enough of certain blood proteins, such as albumin.Enlarged spleen (splenomegaly). Portal hypertension can also cause changes and swelling in the spleen and inclusions of white blood cells and platelets. A decrease in the number of white blood cells and platelets in the blood can be the first sign of cirrhosis.

bleeding. Portal hypertension can cause blood to be diverted into smaller veins.With the added pressure, these smaller veins can rupture and cause severe bleeding. Portal hypertension can cause enlarged veins (varices) in the esophagus (esophageal varices) or in the stomach (gastric varices) and lead to life-threatening bleeding. Failure of the liver to make enough clotting factors can also contribute to persistent bleeding.

infections. When you have cirrhosis, your body may have trouble fighting infection.Ascites can lead to bacterial peritonitis, a serious infection.

Malnutrition. Cirrhosis can make it harder for your body to process nutrients, leading to weakness and weight loss.

Accumulation of toxins in the brain (hepatic encephalopathy). A liver damaged by cirrhosis cannot remove toxins from the blood as well as a healthy liver.These toxins can build up in the brain, causing brain fog and difficulty concentrating. Over time, hepatic encephalopathy can progress to unresponsiveness or coma.

jaundice. Jaundice occurs when the diseased liver doesn’t remove enough bilirubin, a waste product, from the blood. Jaundice causes yellowing of the skin and whites of the eyes and darkening of the urine.bone disease. Some people with cirrhosis lose bone strength and are at increased risk of fractures.

Increased risk of liver cancer. A large proportion of people who develop liver cancer have pre-existing cirrhosis.

Acute in chronic cirrhosis.Some people end up experiencing multiple organ failure. Researchers now believe this is a separate complication in some people with cirrhosis, but they don’t fully understand its causes.

Prevention
Reduce your risk of liver cirrhosis by taking these steps to take care of your liver:

Don’t drink alcohol if you have cirrhosis. If you have liver disease, you should avoid alcohol.
Eat healthy. Choose a plant-based diet rich in fruits and vegetables. Choose whole grains and lean protein sources.Reduce the amount of greasy and fried foods you eat.
Maintain a healthy weight. Too much body fat can damage the liver. Talk to your doctor about a weight loss plan if you’re overweight or obese.
Reduce your risk of hepatitis.Sharing needles and having unprotected sex can increase your risk of hepatitis B and C. Ask your doctor about hepatitis vaccines.

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